The following section contains SPOILERS. It has been hidden from view as to protect users from spoiling themselves. Expand it at your own risk.
Spoilers start here.
Monosuke is destroyed during Kirumi Tojo's execution, as Monodam pushes him in the way of Kirumi's falling corpse, which ends up crushing him in Chapter 2.
Spoilers end here.
Monosuke's appearance is similar to that of his father, Monokuma, but the part that is black on Monokuma consists of yellowish brown and dark brown stripes. Likewise, his left eye is white, contrasting Monokuma's. He has bright pink cheeks and eyelashes on his right eye.
He dons a pair of round black glasses, an abacus, and a yellow pacifier.
Monosuke is a child-like robot. He is the most cool-headed in the group and appears to be the most intelligent as well. However, he is neither mature nor docile, and he has a horrible mouth similar to Monokid.
He acts like the straight man of a double act stand-up comedy. He often displays a positive attitude even in the middle of an argument between members. He tends to be the one correcting his siblings whenever they say something nonsensical.
Being a Monokuma, he enjoys killing and gore, though he acts more calm about it than overly excited Monokid.
Monokuma is the self-proclaimed father of Monosuke, Monotaro, Monokid, Monodam and Monofunny. He calls them his "adorable children", but apparently he also has a tendency to punch them if they annoy him. Considering himself the Headmaster, Monokuma seems annoyed if his children try to steal the show.
Monosuke's name could come from the ancient title of Kokushi (often said as no suke when addressing an official with the title.
A main job of those entitled to Kokushi is keeping track of taxes, which an abacus can be used to help with, something Monosuke has.
Monosuke as a character is strongly associated with the Osaka area of Japan.
He is portrayed as the "straight man" (tsukkomi 突っ込み) of Manzai, a form of Japanese comedy that has been developed in Osaka. He calls other people "funny man" (boke ボケ), the other performer of the double act.
He speaks with Osaka-ben, the specific dialect of Kinki Japanese spoken in the Osaka area. Because of associations with Manzai comedy, the speakers are often viewed as being more funny or talkative than typical speakers of other dialects.
His tiger-striped pattern is a reference to Hanshin Tigers, the Osaka baseball team.
His glasses are a reference to the ones of Kuidaore Taro, a mechanical drum-playing clown in front of Cui-daore, a restaurant in one of the principal tourist destinations in Osaka.
Despite being a robot, he appears to have a very poor eyesight without his glasses.