Ultimate Despair are described as despair made human and their goal is to make the entire world despair.
After their leader died in The Ultimate Punishment, most of the members followed her example and committed suicide. The ones who survived became known as the Remnants of Despair and hacked up Junko's body and attached many of her body parts onto themselves.
They did various things for the sake of despair and Junko Enoshima: starved themselves till their bodies were husks, some offered up their parents to Junko to use for experiments on murder, others slaughtered innocent civilians and forced them to kill themselves as a tribute to their dead leader, one removed their own eye and replaced it with Junko's, possibly to see her despair. It is also said members of Ultimate Despair attempted to produce children with Junko's corpse. It is notable that Nagito Komaeda took her left hand, although it does not function. They also started The Tragedy and kept it ongoing even after their leader's death.
Eventually, the Future Foundation secured their custody - at first only aware that they were survivors from Hope's Peak Academy. When Makoto Naegi and the 14th Division of the Future Foundation realized that the survivors were in fact members of Ultimate Despair, the survivors were made to enter the Neo World Program, where their memories were reset to before they were manipulated by Junko - generally resulting in them not recognizing each other. The plan was to overwrite their memories with good ones, to undo all the damage Junko had done to them.
Unfortunately this plan ended in failure, due to Junko's interference as a virus AI, uploaded into the program by Izuru Kamukura before they were put into the program. As a result, they ended up experiencing much of the same violent events as the "Class of 78" did.
The ending of the Danganronpa 2: Goodbye Despair heavily implied that even though the Neo World Program did not successfully erase any memories at all, the remnants of Ultimate Despair may have kept their memories from inside the Neo World Program and were able to recant their status as Ultimate Despair. The surviving Remnants of Despair currently reside on Jabberwock Island and are attempting to find a way to awaken their comatose friends, while the Future Foundation left them alone and continued cleaning up the world and putting an end to The Tragedy.
|Junko Enoshima||Ultimate Fashionista||Founder/Dead|
|Monokuma||Hope's Peak Academy Headmaster||Active|
|Izuru Kamukura/Hajime Hinata||Ultimate Hope (Former)/???||Former/Alive|
|Nagito Komaeda*||Ultimate Lucky Student||Comatose|
|Mikan Tsumiki*||Ultimate Nurse||Comatose|
|Fuyuhiko Kuzuryu||Ultimate Yakuza||Former/Alive|
|Sonia Nevermind||Ultimate Princess||Former/Alive|
|Akane Owari||Ultimate Gymnast||Former/Alive|
|Kazuichi Soda||Ultimate Mechanic||Former/Alive|
|Nekomaru Nidai*||Ultimate Team Manager||Comatose|
|Peko Pekoyama*||Ultimate Swordswoman||Comatose|
|Teruteru Hanamura*||Ultimate Cook||Comatose|
|Hiyoko Saionji*||Ultimate Traditional Dancer||Comatose|
|Ibuki Mioda*||Ultimate Musician||Comatose|
|Gundham Tanaka*||Ultimate Breeder||Comatose|
|Mahiru Koizumi*||Ultimate Photographer||Comatose|
|Byakuya Togami (Danganronpa 2)*||Ultimate Affluent Progeny (Imposter)||Comatose|
(Whether the members in comatose will wake up or denounce their status as Ultimate Despair is unknown.)